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7-Ketolithocholic acid

CAS No. 4651-67-6

7-Ketolithocholic acid ( 3α-Hydroxy-7-oxo-5β-cholanic acid )

产品货号. M26545 CAS No. 4651-67-6

7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥332 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    7-Ketolithocholic acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.
  • 产品描述
    7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.
  • 同义词
    3α-Hydroxy-7-oxo-5β-cholanic acid
  • 通路
    Proteasome/Ubiquitin
  • 靶点
    Endogenous Metabolite
  • 受体
    PRMT5
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    4651-67-6
  • 分子量
    390.6
  • 分子式
    C24H38O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])C(C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Christopher R. Smith, et al. Abstract LB003: Fragment based discovery of MRTX9768, a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors. Cancer Res 1 July 2021; 81 (13_Supplement): LB003.
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